Abnormal spinal cord morphology Myelopathy This is a descriptive term that should not be used for new annotations. If possible, choose a more precise HPO term that describes the actual observed abnormality.The most frequent etiology of myelopathy is related to degenerative disease of the spine. This can be due to compression of the spinal cord by an osteophyte or extruded disc material in the cervical spine or, less often, in the thoracic spine. Subsequent to degenerative etiology, the next common etiologies are spinal cord compression due to extradural masses caused by metastatic disease to bone or blunt trauma. There are also primary neoplastic, infectious, inflammatory, neurodegenerative, vascular, nutritional, and idiopathic disorders that lead to myelopathy. Myelopathy is an descriptive term, referring to pathology leading to a neurologic deficit related to the spinal cord. The clinical diagnosis of myelopathy requires a detailed history and physical examination to define the clinical syndrome. Neuroimaging is indicated in most instances of new-onset myelopathy. It is indicated also when the worsening of a myelopathy is unexplained. SNOMEDCT_US:48522003 UMLS:C0037928 HP:0002196 Closed neural tube defect