Abnormal small intestine morphology Celiac disease Coeliac disease UMLS:C0007570 Celiac disease (CD) is an autoimmune condition affecting the small intestine, triggered by the ingestion of gluten, the protein fraction of wheat, barley, and rye. Clinical manifestations of CD are highly variable and include both gastrointestinal and non-gastrointestinal features. The hallmark of CD is an immune-mediated enteropathy. This term is included because the occurrence of CD is seen as a feature of a number of other diseases. Celiac disease Celiac sprue SNOMEDCT_US:396331005 Coeliac sprue HP:0002608 Immunologic hypersensitivity