<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/HP?iri=http://purl.obolibrary.org/obo/HP_0002731"?>
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     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- 
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    //
    // Datatypes
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
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    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
        <rdfs:label>inheres in</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label>has modifier</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/GO_0070227 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0070227">
        <rdfs:label>lymphocyte apoptotic process</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0002731 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0002731">
        <rdfs:label>Decreased T cell apoptosis</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
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                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000911"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0070227"/>
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                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
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                    </Class>
                </someValuesFrom>
            </Restriction>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0030886"/>
        <rdfs:comment>Apoptosis, a form of programmed cell death, is an important mechanism that prevents uncontrolled proliferation of activated lymphocytes and regulates lymphocyte homeostasis.</rdfs:comment>
        <oboInOwl:hasExactSynonym>Defective lymphocyte apoptosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C1858969</oboInOwl:hasDbXref>
        <ns4:IAO_0000115>Abnormal decrease of apoptosis by peripheral blood T cells in an in vitro culture, compared to a healthy control sample. May be either spontaneous, induced by UV, X-ray, FasL or other agens. Commonly measured by surface expression of phosphatidyl serine labelled by Annexin V, but other methods such as staning of cleaved Caspases may be used by different laboratories.</ns4:IAO_0000115>
        <oboInOwl:id>HP:0002731</oboInOwl:id>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0030886 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0030886">
        <rdfs:label>Abnormal T cell apoptosis</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000911 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000911">
        <rdfs:label>decreased rate</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



