Arthritis Osteoarthritis Degeneration (wear and tear) of articular cartilage, i.e., of the joint surface. Joint degeneration may be accompanied by osteophytes (bone overgrowth), narrowing of the joint space, regions of sclerosis at the joint surface, or joint deformity. HP:0002824 UMLS:C0029408 Degenerative joint disease SNOMEDCT_US:225655006 HP:0005762 HP:0001379 HP:0002758 SNOMEDCT_US:396275006