Neuroblastoma NCIT:C3270 HP:0006738 Cancer of early nerve cells Neuroblastoma is a solid tumor that originate in neural crest cells of the sympathetic nervous system. Most neuroblastomas originate in the abdomen, and most abdominal neuroblastomas originate in the adrenal gland. Neuroblastomas can also originate in the thorax, usually in the posterior mediastinum. SNOMEDCT_US:87364003 SNOMEDCT_US:432328008 UMLS:C0027819 HP:0003006 Neuroblastic tumor Peripheral primitive neuroectodermal neoplasm