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    <!-- http://purl.obolibrary.org/obo/HP_0003236 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0003236">
        <rdfs:label>Elevated circulating creatine kinase activity</rdfs:label>
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        <oboInOwl:hasExactSynonym>Increased serum CK</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0008164</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>High serum creatine kinase</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Elevated creatine kinase level in blood</oboInOwl:hasExactSynonym>
        <oboInOwl:id>HP:0003236</oboInOwl:id>
        <oboInOwl:hasExactSynonym>Increased creatine phosphokinase</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Increased serum creatine phosphokinase</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Elevated circulating creatine phosphokinase</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0002147</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>HP:0003531</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>HP:0003078</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Increased CPK</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Increased creatine kinase level in blood</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Elevated creatine kinase concentration</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C0151576</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Elevated serum creatine kinase</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Elevated creatine kinase</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0002906</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Elevated serum creatine phosphokinase</oboInOwl:hasExactSynonym>
        <ns5:IAO_0000115>The activity of creatine kinase in the blood circulation is above the upper limit of normal.</ns5:IAO_0000115>
        <oboInOwl:hasExactSynonym>Increased creatine kinase</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Increased creatine kinase concentration</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0003525</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Elevated circulating creatine kinase activity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Increased creatine kinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Elevated blood creatine phosphokinase</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Increased serum creatine kinase</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C0241005</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Elevated serum CPK</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Elevated creatine kinase level</oboInOwl:hasExactSynonym>
        <rdfs:comment>Elevated serum creatine kinase (CK) activity is usually an indicator of muscle damage. Diseases with very high CK values include subtypes of muscular dystrophies, idiopathic inflammatory myopathies and metabolic myopathies. However, a normal or only slightly elevated CK value does not exclude the presence of a myopathy. The normal range in the blood circulation is 34-171 U/l in males and 34-145 U/l in females, but may vary according to the test used.</rdfs:comment>
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        <rdfs:label>Abnormal circulating creatine kinase activity</rdfs:label>
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        <rdfs:label>abnormal</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/PATO_0000470 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000470">
        <rdfs:label>increased amount</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/PR_000050097 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000050097">
        <rdfs:label>creatine kinase (human)</rdfs:label>
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        <rdfs:label>blood</rdfs:label>
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