Low cholesterol esterification rate Cholesterol esterification converts free cholesterol to cholesteryl esters between the carboxylate group of a fatty acid and the hydroxyl group of cholesterol. Esterification allows more cholesterol to be packaged into the interior of lipoproteins. Cholesterol esterification rates can be measured in skin fibroblasts using for instance a non-lipoprotein [3H]cholesterol source. HP:0003349 UMLS:C1843371 A reduction in the rate of cholesterol esterification. Abnormal circulating enzyme concentration or activity