Antinuclear antibody positivity Elevated antinuclear antibody HP:0003493 Antinuclear antibodies (ANAs) are found in patients with a number of different autoimmune diseases, such as systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, polymyositis, scleroderma, Hashimoto's thyroiditis, juvenile diabetes mellitus, Addison disease, vitiligo, pernicious anemia, glomerulonephritis, and pulmonary fibrosis. ANAs can display various staining patterns such as homogeneous or diffuse; speckled; nucleolar; and peripheral or rim. The presence of autoantibodies in the serum that react against nuclei or nuclear components. Antinuclear antibody positive Serum antinuclear antibody Antinuclear antibodies SNOMEDCT_US:165850001 UMLS:C0151480 Autoimmune antibody positivity