Muscle fiber splitting UMLS:C1836057 Fiber splitting or branching is a common finding in human and rat skeletal muscle pathology. Fiber splitting refers to longitudinal halving of the complete fiber, while branching originates from a regenerating end of a necrotic fiber as invaginations of the sarcolemma. In fiber branching, one end of the fiber remains intact as a single entity, while the other end has several branches. Fiber splitting Fibre splitting Muscle fiber splitting HP:0003555 Abnormal muscle fiber morphology