Prominent nasolabial fold Deep nasolabial fold Prominent nasolabial groove Deep smile lines UMLS:C1866487 HP:0005272 Nasolabial crease, prominent Prominent laugh lines Deep nasolabial groove Exaggerated bulkiness of the crease or fold of skin running from the lateral margin of the nose, where nasal base meets the skin of the face, to a point just lateral to the corner of the mouth (cheilion, or commissure). Deep nasolabial crease Prominent smile lines Deep laugh lines Abnormal nasolabial region morphology