<?xml version="1.0"?>
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     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasAlternativeId"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000066 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000066">
        <rdfs:label>occurs in</rdfs:label>
        <rdfs:label xml:lang="en">occurs in</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
        <rdfs:label>inheres in</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label>has modifier</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
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     -->

    


    <!-- http://purl.obolibrary.org/obo/GO_0001503 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0001503">
        <rdfs:label>ossification</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0002683 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0002683">
        <rdfs:label>Abnormal calvaria morphology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0004331 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0004331">
        <rdfs:label>Decreased skull ossification</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0005474 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0005474">
        <rdfs:label>Decreased calvarial ossification</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002302"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                                <someValuesFrom>
                                    <Class>
                                        <intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0001503"/>
                                            <Restriction>
                                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004339"/>
                                            </Restriction>
                                        </intersectionOf>
                                    </Class>
                                </someValuesFrom>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002683"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004331"/>
        <oboInOwl:hasAlternativeId>HP:0002701</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>HP:0002702</oboInOwl:hasAlternativeId>
        <rdfs:comment>A hypomineralised skull castes little or no acoustic shadow on prenatal ultrasound. This makes visualization of the intracranial anatomy clearer than normal. In conditions associated with profound hypomineralisation, the skull shape can be distorted by pressure from the ultrasound transducer later in pregnancy.</rdfs:comment>
        <oboInOwl:hasAlternativeId>HP:0005454</oboInOwl:hasAlternativeId>
        <oboInOwl:hasRelatedSynonym>Skull soft on palpation</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>Soft skullcap</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Soft calvaria</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Undermineralized calvarium</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Poorly ossified calvarium</oboInOwl:hasExactSynonym>
        <oboInOwl:id>HP:0005474</oboInOwl:id>
        <oboInOwl:hasExactSynonym>Poorly ossified calvaria</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>Abnormal reduction in ossification of the calvaria (roof of the skull consisting of the frontal bone, parietal bones, temporal bones, and occipital bone).</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>UMLS:C1833762</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>HP:0005471</oboInOwl:hasAlternativeId>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0002302 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002302">
        <rdfs:label>decreased process quality</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004339 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004339">
        <rdfs:label>vault of skull</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



