<?xml version="1.0"?>
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     xml:base="http://www.w3.org/2002/07/owl"
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     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
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    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
        <rdfs:label>inheres in</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label>has modifier</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/GO_0070166 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0070166">
        <rdfs:label>enamel mineralization</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0000682 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0000682">
        <rdfs:label>Abnormal dental enamel morphology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0006285 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0006285">
        <rdfs:label>Enamel hypomineralization</rdfs:label>
        <equivalentClass>
            <Restriction>
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                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000911"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000682"/>
        <oboInOwl:hasNarrowSynonym>Increased porosity of tooth enamel</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>UMLS:C3665628</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>HP:0006359</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Poorly mineralized tooth enamel</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>White spot lesions of tooth enamel</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>Decreased enamel mineralisation</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>Fluorosis of tooth enamel</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>HP:0006285</oboInOwl:id>
        <oboInOwl:hasDbXref>SNOMEDCT_US:109487003</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Hypomineralization of enamel</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>A decreased amount of enamel mineralization. Hypomineralized enamel has a brown discoloration and brittle aspect.</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>UMLS:C4280460</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Mottled tooth enamel</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C4280461</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C4280253</oboInOwl:hasDbXref>
        <rdfs:comment>Enamel hypomineralization can be caused by genetic or environmental factors. It may occur in both deciduous and permanent dentitions, although more often in the permanent dentition. It may concern a single tooth, several teeth, or the complete dentition and may affect part or the complete surface of the tooth. Enamel hypomineralization is a qualitative defect of enamel, in which the enamel can be rough and softer. Affected teeth may be sensitive. Enamel hypomineralization can be part of molar incisor hypomineralization (hypomineralisation of systemic origin of one to four permanent first molars, frequently associated with affected incisors) and of hypomineralized second primary molars (or deciduous molar hypomineralisation, which indicates idiopathic hypomineralization of one to four second deciduous molars).</rdfs:comment>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000911 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000911">
        <rdfs:label>decreased rate</rdfs:label>
    </Class>
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