<?xml version="1.0"?>
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     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasAlternativeId"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- 
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    //
    // Datatypes
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
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    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000066 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000066">
        <rdfs:label>occurs in</rdfs:label>
        <rdfs:label xml:lang="en">occurs in</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

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        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
        <rdfs:label>inheres in</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label>has modifier</rdfs:label>
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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/GO_0043473 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0043473">
        <rdfs:label>pigmentation</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0000479 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0000479">
        <rdfs:label>Abnormal retinal morphology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0007703 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0007703">
        <rdfs:label>Abnormal retinal pigmentation</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000001"/>
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                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
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                                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0043473"/>
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                                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001782"/>
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                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
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        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000479"/>
        <oboInOwl:id>HP:0007703</oboInOwl:id>
        <oboInOwl:hasAlternativeId>HP:0007743</oboInOwl:hasAlternativeId>
        <ns4:IAO_0000115>Any deviation from the normal pigmentation of the retina.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>Abnormality of RPE</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Abnormality of retinal pigment epithelium</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>SNOMEDCT_US:421689001</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Retinal pigmentary anomaly</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C1862475</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C1720508</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>HP:0008051</oboInOwl:hasAlternativeId>
        <oboInOwl:hasRelatedSynonym>Abnormality of the retinal pigment epithelium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>Abnormality of retinal pigmentation</oboInOwl:hasExactSynonym>
        <rdfs:comment>This includes abnormalities of the pigmentation of the RPE and intraretinal pigment migration. An abnormality of the retina characterized by pigment deposition. It is typically associated with migration and proliferation of macrophages or retinal pigment epithelial cells into the neuroretina; melanin from these cells causes the pigmentary changes. Pigmentary retinopathy is a common final pathway of many retinal conditions and is often associated with visual loss.</rdfs:comment>
        <oboInOwl:hasAlternativeId>HP:0007741</oboInOwl:hasAlternativeId>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000001 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000001">
        <rdfs:label>quality</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001782 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001782">
        <rdfs:label>pigmented layer of retina</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



