<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/HP?iri=http://purl.obolibrary.org/obo/HP_0010976"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:dcterms="http://purl.org/dc/terms/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/terms/creator"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasAlternativeId"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/terms/date"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
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    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
        <rdfs:label>inheres in</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label>has modifier</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
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    <!-- http://purl.obolibrary.org/obo/CL_0000236 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000236">
        <rdfs:label>B cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0010976 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0010976">
        <rdfs:label>Decreased total B cell count</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0001997"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000236"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0025806"/>
        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-02-06T09:44:11Z</dcterms:date>
        <oboInOwl:hasAlternativeId>HP:0002956</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>HP:0002856</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>UMLS:C1855067</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Low B cell count</oboInOwl:hasExactSynonym>
        <rdfs:comment>Plasma B cells differentiate from B cells and secrete large amounts of antibodies.</rdfs:comment>
        <oboInOwl:hasAlternativeId>HP:0005365</oboInOwl:hasAlternativeId>
        <ns4:IAO_0000115>The absolute number of B cells in the blood, per microlitre is below the lower limit of normal of the reference range for the appropriate sex and age-group.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>B lymphocytopenia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0030251</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Decreased B cell count</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Reduction in B cell number</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>B cell lymphopenia</oboInOwl:hasExactSynonym>
        <oboInOwl:id>HP:0010976</oboInOwl:id>
        <oboInOwl:hasNarrowSynonym>CD19 lymphocytes low</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasExactSynonym>B cell deficiency</oboInOwl:hasExactSynonym>
        <dcterms:creator rdf:resource="https://orcid.org/0000-0002-0736-9199"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0025806 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0025806">
        <rdfs:label>Abnormal total B cell count</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0001997 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001997">
        <rdfs:label>decreased amount</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



