Abnormal Descemet membrane morphology Corneal guttata 2012-07-27T02:06:24Z HP:0012038 Corneal endothelial guttata Corneal guttata are often observed in elderly people and are known to be associated with Fuchs corneal endothelial dystrophy, and also with trauma, congenital glaucoma, and macular dystrophy. SNOMEDCT_US:373424008 UMLS:C0271288 Corneal guttata are droplet-like accumulations of non-banded collagen on the posterior surface of Descemet's membrane. The presence of focal thickenings of Descemet's membrane histologically named guttae. Cornea guttata can be easily diagnosed in vivo and ex vivo by means of specular microscopy as it gives dark areas where no endothelial cells are visible. Corneal guttae