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    <!-- http://purl.obolibrary.org/obo/HP_0002315 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0002315">
        <rdfs:label>Headache</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/HP_0012199 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0012199">
        <rdfs:label>Cluster headache</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002315"/>
        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2013-03-12T11:37:40Z</dcterms:date>
        <oboInOwl:id>HP:0012199</oboInOwl:id>
        <oboInOwl:hasDbXref>ICD-10:G44.0</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>A type of headache characterized by repeated attacks of unilateral pain lasting 15 to 180 minutes and associated with local autonomic signs.</ns3:IAO_0000115>
        <oboInOwl:hasDbXref>SNOMEDCT_US:193031009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US:193947008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US:230473009</oboInOwl:hasDbXref>
        <rdfs:comment>According to the International Classification of Headache Disorders (ICHD-II), the diagnosis of cluster headache can be made with at least five attacks fulfilling criteria B-D: (B) Severe or very severe unilateral orbital, supraorbital and/or temporal pain lasting 15-180 minutes if untreated. (C) Headache is accompanied by at least 1 of the following: (i) Ipsilateral conjunctival injection and/or lacrimation. (ii) Ipsilateral nasal congestion and/or rhinorrhea. (iii) Ipsilateral eyelid edema. (iv) Ipsilateral forehead and facial sweating. (v) Ipsilateral miosis and/or ptosis. (vi) A sense of restlessness or agitation. (D) Attacks have a frequency from 1 every other day to 8/day. Additionally, the headaches cannot attributed to another disorder.</rdfs:comment>
        <oboInOwl:hasDbXref>UMLS:C0009088</oboInOwl:hasDbXref>
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