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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <!-- http://purl.obolibrary.org/obo/HP_0006247 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0006247">
        <rdfs:label>Enlarged interphalangeal joints</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0012313 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0012313">
        <rdfs:label>Heberden node</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0006247"/>
        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2013-08-10T12:19:59Z</dcterms:date>
        <oboInOwl:hasDbXref>UMLS:C0018862</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US:371598009</oboInOwl:hasDbXref>
        <rdfs:comment>Heberden&#39;s nodes are nodular deformities at the distal interphalangeal joint of the fingers (usually the middle and index) and are commonly seen in the elderly. The deformity is created by osteophyte formation and synovial thickening at the margin ofan osteoarthritic joint. Significant functional problems are rarely encountered though patients may suffer with stiffness and pain. Surgical intervention is seldom indicated unless there is severe pain or instability. In such cases, a joint fusion may be appropriate.</rdfs:comment>
        <oboInOwl:hasExactSynonym>Heberden&#39;s node</oboInOwl:hasExactSynonym>
        <oboInOwl:id>HP:0012313</oboInOwl:id>
        <ns3:IAO_0000115>Bony swelling of the distal interphalangeal joint (DIP) associated with the formation of osteophytes (calcific spurs) of the articular (joint) cartilage that are visible radiographically.</ns3:IAO_0000115>
        <dcterms:creator rdf:resource="https://orcid.org/0000-0002-0736-9199"/>
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