Abnormal lymph-node tissue architecture Compressed lymph-node sinuses 2023-11-10T20:14:01Z Lymph node sinuses are structures that carry fluid and some cells traveling to and from the lymph node parenchyma, and often contain some histiocytes. These are normally patent but may be compressed by proliferating or infiltrating cells such as lymphoma to the point where they are no longer visible on routine H&E stained sections. Loss of the typical patency (openness) of lymph node sinuses.