Edema Fetal skin edema 2022-01-22T07:37:48Z In first trimester ultrasound examination generalized skin edema is often the first feature of hydrops fetalis. A separation of skin in one or more regions of the body or even along the entire length of body wall (to a degree greater than gestational-age related norms) related to pathologically increased fluid accumulation in the subcutaneous tissue. Abnormal fetal skin morphology