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    <!-- http://purl.obolibrary.org/obo/HP_0008064 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0008064">
        <rdfs:label>Ichthyosis</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/HP_0025810 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0025810">
        <rdfs:label>Ichthyosis linearis circumflexa</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0008064"/>
        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2025-04-17T16:14:38Z</dcterms:date>
        <ns3:IAO_0000115>A type of ichthyosis characterized by migratory, annular and polycyclic erythematous patches with double-edged scales at the periphery of the lesions.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>Double-edged scaling</oboInOwl:hasExactSynonym>
        <oboInOwl:hasBroadSynonym>Serpiginous scaling</oboInOwl:hasBroadSynonym>
        <rdfs:comment>The erythematous patch (flat area of redness 1 cm or more in width) that is ring-shaped (annular) or serpiginous (with multiple ring-shaped lesions (polycyclic). The lesions are bordered by two distinct rings of scale at their outer edges (double-edged). The distribution of the lesions changes with time (migratory). Ichthyosis linearis circumflexa (ILC) may rarely be observed as an isolated lesion, but is a characteristic manifestation of Netherton syndrome. Lesions are often described as serpiginous scaling or double-edged scaling.</rdfs:comment>
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