Abnormal neutrophil physiology Decreased neutrophil adhesion 2025-04-27T05:27:38Z Neutrophil firm adhesion to endothelial cells (EC) is a highly regulated process and plays an essential role in inflammatory responses3,4. The firm adhesion of neutrophil follows initial neutrophil rolling and capture on the EC and ultimately can result in transmigration in vivo. Impaired leukocyte adhesion HP:0033798 Abnormal decrease of neutrophil adhesion capacity, commonly measured as surface expression of CD18, CD11a or CD11b using flow cytometry.