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    <!-- http://purl.obolibrary.org/obo/HP_0010876 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0010876">
        <rdfs:label>Abnormal circulating protein concentration</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0031029 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0031029">
        <rdfs:label>Elevated circulating CEA concentration</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010876"/>
        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-05-27T10:48:16Z</dcterms:date>
        <rdfs:comment>Carcinoembryonic antigen (CEA) is a member of the immunoglobulin supergene family. The human CEA gene family is clustered on chromosome 19q and comprises 29 genes. CEA is highly expressed in embryonic tissue and in some cancers, and is a widely used tumor marker.</rdfs:comment>
        <oboInOwl:hasExactSynonym>Elevated carcinoembryonic antigen level</oboInOwl:hasExactSynonym>
        <ns3:IAO_0000115>The concentration of CEA (carcinoembryonic antigen) in the blood circulation is above the upper limit of normal.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>Increased plasma CEA</oboInOwl:hasExactSynonym>
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