Abnormal endocrine physiology Inappropriate antidiuretic hormone secretion 2017-07-02T11:46:17Z Inappropriate ADH secretion Common etiologies of inappropriate antidiuretic hormone (ADH) secretion include nervous system disease, cancer, pulmonary disease, and as a side effect of a medication. This term is meant to refer to the inappropriately high level of ADH and not to the full syndrome of inappropriate antidiuretic hormone secretion (SIADH), which is considered a disease entity rather than a phenotypic feature. A state of increased circulating antidiuretic hormone despite hyponatremia and hypo-osmolality with normal or increased plasma volume. SIADH Syndrome of inappropriate antidiuretic hormone secretion