Abnormal liver parenchyma morphology Periportal emperipolesis 2019-01-21T01:20:50Z Emperipolesis is derived from the Greek (em-inside; peri-around; polemai-wander about) and is as the active penetration of one cell by another which remains intact. It differs from phagocytosis in that an engulfed cell exists temporarily within another cell and with an intact normal structure while in phagocytosis, the engulfed cell is destroyed by the protective action of lysosomal enzymes. The engulfing of lymphocytes by hepatocytes, which typically occurs in the interface hepatitis area.