part of part of has part has part characteristic of inheres in has modifier isovaleric acid Abnormal circulating short-chain fatty-acid concentration Increased circulating isovaleric acid concentration 2020-09-19T11:42:45Z Increased concentration of isovaleric acid, a C5, branched-chain saturated fatty acid, in the blood concentration. Increased circulating isovalerate In individuals with the disease isovaleric acidemia (OMIM:243500), free isovaleric acid in blood during episodes of acute metabolic decompensation can reach several hundred times normal values but is not readily seen in blood and urine due to its rapid conjugation to other compounds. Thus, isovalerylcarnitine and isovalerylglycine are the hallmarks of this disorder in plasma and urine, respectively, and are elevated regardless of the metabolic condition of the affected individual. Isovalericacidemia abnormal increased amount blood