<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/HP?iri=http://purl.obolibrary.org/obo/HP_0033305"?>
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     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:dcterms="http://purl.org/dc/terms/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
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    //
    // Annotation properties
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/terms/creator"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/terms/date"/>
    


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    // Datatypes
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
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    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>part of</rdfs:label>
        <rdfs:label xml:lang="en">part of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
        <rdfs:label>inheres in</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label>has modifier</rdfs:label>
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    <!-- 
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    //
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    <!-- http://purl.obolibrary.org/obo/HP_0010876 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0010876">
        <rdfs:label>Abnormal circulating protein concentration</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0033305 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0033305">
        <rdfs:label>Abnormal circulating fetuin-A concentration</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
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                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000070"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                                <someValuesFrom>
                                    <Class>
                                        <intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PR_P02765"/>
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                                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
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                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
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                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010876"/>
        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-11-28T22:09:58Z</dcterms:date>
        <ns4:IAO_0000115>Any deviation from the normal concentration of fetuin-A in the blood circulation.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>Abnormal circulating fetuin-A concentration</oboInOwl:hasExactSynonym>
        <rdfs:comment>Fetuin-A (FetA) is a 64-kDa glycoprotein that is found in relatively high concentrations in human serum. In human adults, FetA is mainly expressed and secreted from the liver and adipose tissue. Epidemiologic research consistently observes elevated circulating FetA in obesity and related complications, such as type 2 diabetes mellitus, the metabolic syndrome, and nonalcoholic fatty liver disease.</rdfs:comment>
        <oboInOwl:hasExactSynonym>Abnormal alpha-2-HS-glycoprotein level</oboInOwl:hasExactSynonym>
        <dcterms:creator rdf:resource="https://orcid.org/0000-0002-0736-9199"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000070 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000070">
        <rdfs:label>amount</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_P02765 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_P02765">
        <rdfs:label>alpha-2-HS-glycoprotein (human)</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000178 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178">
        <rdfs:label>blood</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



