Severe cytomegalovirus infection Cytomegalovirus colitis 2021-01-09T17:55:07Z CMV colitis A form of cytomegalovirus infection characterized by infection and inflammation of the colon. Patients with CMV colitis present with non-specific symptoms, including diarrhea, abdominal pain, fever, rectal bleeding, and weight loss. Hematochezia and diarrhea are the most frequently observed symptoms in these patients. Cytomegalovirus colitis occurs most commonly in immunocompromised hosts, including acquired immunodeficiency syndrome (AIDS), organ transplantation, hematological malignancy, cancer therapy, and corticosteroid therapy. Opportunistic viral infection