Abnormal pulmonary thoracic imaging finding Beaded septum sign 2021-02-24T13:44:52Z Irregular and nodular thickening of interlobular septa reminiscent of a row of beads. The beaded septum sign is frequently seen in lymphangitic spread of cancer and less often in sarcoidosis. See Figure 10 of Hansell DM, et al., Fleischner Society: glossary of terms for thoracic imaging. Radiology. 2008;246:697-722.