Abnormal morphology of the limbic system Abnormal amygdala morphology 2021-02-28T14:53:43Z A structural anomaly of the amygdala. Abnormal morphology of the amygdala The amygdala is a centrally located brain region that plays fundamental roles in human emotion, memory, and various homeostatic responses. Situated in the rostral part of the temporal lobe and abutting the basal forebrain, the human amygdala is closely connected with olfactory structures, the hippocampal formation, basal ganglia, basal forebrain components including ventral striatum and nucleus basalis, insula, claustrum, hypothalamus, and various thalamic nuclei. The amygdala contributes to white matter tracts that stream nearby, including the anterior commissure, inferior longitudinal fasciculus, stria terminalis, and uncinate fasciculus.