Abnormal spleen morphology Splenic infarction 2022-09-04T12:24:15Z Ischemia and necrosis of part or all of the spleen resulting from compromise of blood supply resulting from arterial or venous occlusion. Spleen infarction Spleen infarct Splenic infarction may be global or involve a segment of the spleen depending on which vessel is occluded. Typical presentation includes left sided abdominal pain in a person with an underlying hematologic disorder, hypercoagulable state, blood-borne malignancy, blunt abdominal trauma, or embolic illness. Splenic infarct