<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/HP?iri=http://purl.obolibrary.org/obo/HP_0040087"?>
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     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:dcterms="http://purl.org/dc/terms/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/terms/creator"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
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    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>part of</rdfs:label>
        <rdfs:label xml:lang="en">part of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
        <rdfs:label>inheres in</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label>has modifier</rdfs:label>
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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/CHEBI_27470 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_27470">
        <rdfs:label>folic acid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0012335 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0012335">
        <rdfs:label>Abnormality of folate metabolism</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0040087 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0040087">
        <rdfs:label>Abnormal blood folate concentration</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
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                                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_27470"/>
                                            <Restriction>
                                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
                                            </Restriction>
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                                </someValuesFrom>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
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                    </Class>
                </someValuesFrom>
            </Restriction>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012335"/>
        <oboInOwl:hasExactSynonym>Abnormality of folate in blood</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>Any deviation from the normal concentration of folate in the blood circulation.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>Abnormal serum folate</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C4021037</oboInOwl:hasDbXref>
        <rdfs:comment>Folate is an essential water-soluble vitamin (vitamin B9) that is found in green leafy vegetables, cereals, legumes, and fruit. As a major methyl group donor, it plays an important role in one-carbon metabolism and is involved in DNA, RNA, and protein synthesis, in addition to its significant role in energy production and normal cell division. Low blood folate concentration is associated with an increased risk for neural tube defects during pregnancy.</rdfs:comment>
        <dcterms:creator rdf:resource="https://orcid.org/0000-0002-5316-1399"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000070 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000070">
        <rdfs:label>amount</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000178 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178">
        <rdfs:label>blood</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



