Thickened skin Scleroderma 2010-08-10T04:14:42Z HP:0007426 A chronic autoimmune phenomenon characterised by fibrosis (or hardening), vascular alterations, and autoantibodies. Sclerosis of the skin occurs in association with disorders as diverse as mixed connective tissue disease and systemic sclerosis. This term is intended to represent the phenotypic feature scleroderma rather than a particular disease. HP:0001594 SNOMEDCT_US:403524003 Pseudoscleroderma UMLS:C1274865 A chronic autoimmune phenomenon characterized by fibrosis (or hardening) and vascular alterations of the skin. HP:0100324 UMLS:C0011644 Progressive systemic scleroderma SNOMEDCT_US:89155008