Lipodystrophy Lipoatrophy 2010-12-27T12:55:33Z Loss of fat tissue in localised area HP:0100578 MEDDRA:10024604 SNOMEDCT_US:248315005 This may occur as a result of subcutanous injections of insulin in the treatment of diabetes, from the use of human growth hormone or from subcutanous injections of Copaxone used for the treatment of multiple sclerosis. In the latter case, an injection may produce a small dent at the injection site. Lipoatrophy is also an adverse drug reaction that is associated with some antiretroviral drugs. Localized loss of fat tissue. Atrophy of fat UMLS:C1280433 Loss of fat tissue in localized area