Barrett esophagus 2010-12-27T01:33:00Z The medical significance of Barrett esophagus is its strong association with esophageal adenocarcinoma, a particularly lethal cancer. Barret syndrome Endobrachyesophagus UMLS:C0004763 Barrett oesophagus Barrett's esophagus HP:0100580 SNOMEDCT_US:302914006 Barrett's oesophagus An abnormal change (metaplasia) in the cells of the inferior portion of the esophagus. The normal squamous epithelium lining of the esophagus is replaced by metaplastic columnar epithelium. Columnar epithelium refers to a cell type that is typically found in more distal parts of the gastrointestinal system. Esophageal neoplasm