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    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000084">
        <rdfs:label>T cell</rdfs:label>
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        <rdfs:label>CD4-positive, alpha-beta memory T cell</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/HP_0031392 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0031392">
        <rdfs:label>Abnormal CD4+ T cell subset proportion</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/HP_0032182 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0032182">
        <rdfs:label>Abnormal memory T cell proportion</rdfs:label>
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        <rdfs:label>Abnormal CD4+ memory T cell proportion</rdfs:label>
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        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-04-05T15:04:39Z</dcterms:date>
        <rdfs:comment>Unlike in CD8+ T cells, in CD4+ T cells the populations of central memory, effector memory and TEMRA cells are not easily measurable and or are of limited clinical utility. Therefore, generally, only the distinction between naive and memory CD4 T cells is made.</rdfs:comment>
        <oboInOwl:hasExactSynonym>Abnormal CD4+ memory T cell proportion</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0410381</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>HP:0410382</oboInOwl:hasAlternativeId>
        <ns4:IAO_0000115>Abnormal increase or decrease of the memory CD4+ T cell subpopulation, commonly characterized as CD45RA-, CD45RO+, or CD27-, measured as percentage of total CD4+ T cells in the blood, compared to a reference range for a given sex and age-group.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>Abnormal proportion of CD4-positive memory T cells</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0025623</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Abnormal proportion of CD4+ memory T cells</oboInOwl:hasExactSynonym>
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