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    <!-- http://purl.obolibrary.org/obo/HP_0410386 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0410386">
        <rdfs:label>Decreased CD4+ memory T cell proportion</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/HP_0410388 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0410388">
        <rdfs:label>Decreased proportion of central memory CD4-positive T cells</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0410386"/>
        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-04-05T15:28:40Z</dcterms:date>
        <ns3:IAO_0000115>A reduced proportion of central memory CD4-positive memory T cells compared to the total number of T cells in the blood. These cells have the phenotype of CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>Decreased proportion of CD4+ central memory cells</oboInOwl:hasExactSynonym>
        <rdfs:comment>An abnormally decreased proportion of central memory CD4+ T cells. These are memory cells that are located in the secondary lymphoid organs. These cells may have a CD3/CD4/CD62L+/CD45RA- phenotype.</rdfs:comment>
        <oboInOwl:hasExactSynonym>Decreased proportion of CD4-positive central memory cells</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0025622</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Reduced proportion of CD4+ central memory cells</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Decreased proportion of central memory CD4+, alpha-beta T cell</oboInOwl:hasExactSynonym>
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