<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/HP?iri=http://purl.obolibrary.org/obo/HP_0500266"?>
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     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:dcterms="http://purl.org/dc/terms/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
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    //
    // Annotation properties
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/terms/creator"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/terms/date"/>
    


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    // Datatypes
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
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    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>part of</rdfs:label>
        <rdfs:label xml:lang="en">part of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
        <rdfs:label>inheres in</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/RO_0002503 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002503">
        <rdfs:label>towards</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label>has modifier</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
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    <!-- http://purl.obolibrary.org/obo/CL_0000084 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000084">
        <rdfs:label>T cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0001062 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0001062">
        <rdfs:label>effector memory CD8-positive, alpha-beta T cell, terminally differentiated</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0020177 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0020177">
        <rdfs:label>Abnormal proportion of CD8-positive TEMRA T cells</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0410385 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0410385">
        <rdfs:label>Decreased CD8+ memory T cell proportion</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0500266 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0500266">
        <rdfs:label>Decreased proportion of CD8+ TEMRA T cells</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0040042"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
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                                    <Class>
                                        <intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0001062"/>
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                                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
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                                </someValuesFrom>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002503"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000084"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0020177"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0410385"/>
        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-05-15T19:36:00Z</dcterms:date>
        <oboInOwl:hasExactSynonym>Decreased proportion effector memory CD8-positive, alpha-beta T cells, terminally differentiated</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Decreased proportion of CD8-positive TEMRA T cells</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>An decreased proportion of CD8-positive effector memory RA TEMRA T cells compared to the total number of T cells in the blood. These cells have the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>Decreased CD8+ TEMRA T cell proportion</oboInOwl:hasExactSynonym>
        <dcterms:creator rdf:resource="https://orcid.org/0000-0001-7941-2961"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0040042 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0040042">
        <rdfs:label>decreased ratio</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000178 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178">
        <rdfs:label>blood</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



