Autoimmune antibody positivity Anti-voltage-gated potassium channel antibody positivity 2023-02-17T22:35:59Z Voltage-gated potassium channels represent a family of transmembrane channels responsible for returning the depolarized cell to a resting state after each nerve impulse. Voltage gated potassium channel antibodies in blood The presence of autoantibodies (immunoglobulins) in the serum that react against a voltage-gated potassium channel.