Abnormal intrahepatic bile duct morphology Hepatolithiasis 2023-12-30T23:26:21Z Hepatolithiasis is benign in nature, but the prognosis is poor due to an association with recurrent cholangitis, biliary strictures, liver abscesses, and atrophy or cirrhosis of the affected liver. Hepatolithiasis is also a known risk factor for intrahepatic cholangiocarcinoma. The presence of gallstones within the intrahepatic bile ducts proximal to the right and left hepatic ducts.