Abnormal hepatocyte morphology Mallory bodies 2024-03-07T10:29:04Z Mallory-Denk bodies Mallory bodies were once thought to be specific for alcoholic hepatitis but now are known to occur in other liver diseases which include nonalcoholic steatohepatitis, cholestatic liver diseases, primary biliary cirrhosis and hepatocellular carcinoma. Cytoplasmic hyaline inclusions of hepatocytes that are predominantly filamentous ranging from a diameter of 3 to 24 nm vs. 10 nm of classical IF. Mallory-Denk bodies can be classified as type I (parallels filaments), II (randomly orient filaments), or III (granular and amorphous). Type II occurs in the periphery while type III occurs around the center. MDB occur in ballooned hepatocytes.