Abnormal jaw morphology Central giant cell lesion of the jaw 2024-05-08T18:55:23Z These lesions occur more frequently in the mandible than in the maxilla, and occur more frequently on the right side than on the left side. In the maxilla, the lesion may invade the maxillary sinus floor, the orbit and/or nasal passages, which can lead to facial asymmetry, nasal deviation, and mobility of associated dental elements. CGCLs can be classified as aggressive or non-aggressive. A benign proliferative and asymptomatic intraosseous lesion of the jaw formed by fibrous tissue that contains multiple focus of hemorrhage and an aggregation of multinucleated giant cells.