has role T4SS ATPase T4SS ATPase is the enzyme which energizes the T4SS system from the cytoplasm, driving the complex assembly and substrate translocation through the channel. Meng LIU (Mia), Oliver He https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070162/ VirB4 and TraU are the major ATPases founded in ICEs. T4SS ATPase role protein