material entity material entity ICE integration and excision module The integration and excision module refers to those genes and sequence within the ICE responsible for the integration and excision of the element from the host chromosome, including genes encoding the integrase and or recombination directionality factor (also known as excisionase, which influences the direction of recombination mediated by the integrase to favor excision). https://academic.oup.com/nar/article/47/D1/D660/5165266 Meng LIU (Mia), Oliver He recombination module component