serine recombinase https://en.wikipedia.org/wiki/Site-specific_recombination serine recombinase is the second most common integrase seen in T4SS-type ICEs One family of recombinases based on amino acid sequence homology and mechanistic relatedness. Serine is the conserved nucleophilic amino acid residue that serine recombinases use to attack the DNA and which becomes covalently linked to it during strand exchange. Meng LIU (Mia), Oliver He protein