inheres_in disposition material entity protective resistance Lindsay Cowell Albert Goldfain The disposition is realized in a process that mitigates damage to the bearer and has the part as a participant. Alexander Diehl This mitigation sometimes takes the form of protection. CCR5 mutations protect T cells from HIV invasion. If a patient's tumor is resistant to chemotherapy, then the patient is resistant to something beneficial, but the tumor is resistant to something damaging. In this case protective resistance inheres in the tumor's cells and in the tumor, but not in the patient. In some cases, the quality that confers the protective resistance will confer other dispositions that damage the entity, such as is the case with sickle cell trait. A disposition that inheres in a material entity in virtue of the fact that the entity has a part (e.g. a gene product), which itself has a disposition to mitigate damage to the entity. pathogenic disposition invasive disposition collective disposition contagiousness immunocompetence immunosuppressive disposition disposition to form a non-parasitic colony transmissibility disposition disease