coombs test for human brucellosis YL, YH PubMed: 11060059 PubMed: 9684294 The Coombs Test is a diagonostic test using manufactured antigen and antiglobulins to detect the presence of specific antibodies. It is used very commonly in the detection of human brucellosis, but due to expense and time factors is used less often to detect animal brucellosis. Immunoassay test for brucellosis