realized in has disposition at some time agent_in_compromised_process artificially mutated Brucella attenuated disposition mouse - Brucella interaction Brucella omp10 mutant Omp10 is an immunoreactive outer membrane lipoprotein. The omp10 mutant was dramatically attenuated for survival in mice and was defective for growth in minimal medium but was not impaired in intracellular growth in vitro, nor does it display clear modification of the outer membrane properties [Tibor et al., 2002]. see PMID:12228280 Brucella intracellular survival in mouse