has_part has part has_part has disposition at some time attenuated disposition B. suis eryB mutant B. suis 1330 eryB mutant PMID: 10708387 A mutant of strain Brucella suis 1330 that lacks an intact gene eryB. NCBIGene: 1165308 UniProtKB accession: Q8FVH6 The gene eryB from the strain Brucella suis 1330 is a virulence gene. Information about the mutated molecule: MUTATION: EryB is an erythritol phosphate dehydrogenase. The vaccine strain B abortus B19 is the only known B abortus isolate whose growth is inhibited by erythritol. The B abortus B19 strain is an eryCD double mutant. The defect in B19 was complemented in trans by plasmids containing the complete ery region and by plasmids with Tn1725 insertions in eryA, eryB and eryD. Plasmids with Tn1725 insertions in eryC were the only ones that failed to complement the Ery phenotype of B19 [Ref6483:Sangari et al., 2000]. The B. suis eryB mutant by Tn5 transposon mutagenesis was attenuated in the human macrophage -like THP-1 cells. This mutant is sensitive to erythritol and mimics the erythritol sensitive response of the B19 strain [Ref6483:Sangari et al., 2000]. YH eryB glycerol-3-phosphate dehydrogenase