has_part has part has_part has disposition at some time attenuated disposition Brucella purE mutant B. suis 1330 purE mutant UniProtKB accession: Q8FYW3 The gene purE from the strain Brucella suis 1330 is a virulence gene. A mutant of strain Brucella suis 1330 that lacks an intact gene purE. YH Information about the mutated molecule: FUNCTION: This subunit can alone transform AIR to CAIR, but in association with purK, which possesses an ATPase activity, an enzyme complex is produced which is capable of converting AIR to CAIR efficiently under physiological condition (By similarity)(Swiss-Prot: Q8FYW3). CATALYTIC ACTIVITY: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2)(Swiss-Prot: Q8FYW3). PATHWAY: Nucleotide biosynthesis NCBIGene: 1167437 PMID: IMP biosynthesis purE phosphoribosylaminoimidazole carboxylase, catalytic subunit