has_part has part has_part has disposition at some time B. abortus ilvD mutant attenuated disposition B. abortus 2308 ilvD mutant The gene ilvD from the strain Brucella melitensis biovar Abortus 2308 is a virulence gene. PMID: L-isoleucine biosynthesis Information about the mutated molecule: CATALYTIC ACTIVITY: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H(2)O(Swiss-Prot: Q8G353). COFACTOR: Binds 1 4Fe-4S cluster (Potential)(Swiss-Prot: Q8G353). PATHWAY: Amino-acid biosynthesis YH NCBIGene: 3788763 A mutant of strain Brucella melitensis biovar Abortus 2308 that lacks an intact gene ilvD. UniProtKB accession: Q2YNW9 ilvD dihydroxy-acid dehydratase